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Medarex 
EvaluatePharma® delivers unique insight into the past and future performance of companies in the pharmaceutical and biotechnology sector, in a user-friendly, online subscription service.

A small selected sample of reports and related news headlines for Medarex are available below. Free sample reports are also available for other Companies.

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PIPELINE ANALYSIS - Sales Forecasts available to EvaluatePharma Subscribers

 
  Rank Product Therapeutic Category Therapeutic Subcategory Pharmacological Class Phase (Current)
Medarex 1 Valortim Systemic Anti-infectives Anti-bacterials Anti-anthrax MAb Phase I
  - CNTO 148 Musculoskeletal Other anti-rheumatics Anti-TNFa MAb Filed
  - Cancer MAb Project Oncology & Immunomodulators Anti-neoplastic MAbs Anti-cancer MAb Research project

FINANCIAL DATA ($US mln) - Forecasts available to EvaluatePharma Subscribers

Medarex
  2005 2006
 Valuation Measures
  Based on Latest Share Prices
     Valuing the Equity
       Market Capitalisation 1,009 1,009
       PE Ratio (diluted) - Normalised (x) (8.2) (5.3)
 
     Valuing the Enterprise
       Enterprise Value 652 652
       Free Cash Flow (Pre-Dividends) (95) (149)
       FCF Yield (%) (14.6%) (22.8%)
 
 Forecast Financials
  Income Statement
     Total Revenues 51 49
     S,G & A (29) (52)
     R&D (137) (195)
     Other Income/ Expense - Net 4 7
     Associate/ Equity Affiliate Income (6) (1)
     EBIT - Normalised (116) (192)
     Net Interest & Financial Items 11 13
     Pre-tax Profits - Normalised (106) (179)
     Exceptionals (42) (2)
     Income Before Taxes (148) (181)
     Tax 0 0
     Tax Rate (%) 0.2% 0.2%
     Net Income - Reported (148) (182)
     Net Income - Normalised (106) (180)
 
  Per Share Data
     EPS - Diluted (1.34) (1.50)
     EPS - Basic (1.34) (1.50)
     EPS - Normalised (diluted) (0.96) (1.48)
     EPS - Normalised (basic) (0.96) (1.48)
     Avg. Shares Outstanding - Diluted 110.3 121.1
     Avg. Shares Outstanding - Basic 110.3 121.1
     DPS 0.00 0.00

NEWS - Selected Product News Headlines (as of 11 June 2008)

Ofatumumab in Subcutaneous Study in Rheumatoid Arthritis   (Genmab)   10-Jun-2008
Preliminary Data from Ongoing Phase 1 Trial of Investigational Fully Human Anti-PD-1 Antibody “ONO-4538/MDX-1106” Presented at American Society of Clinical Oncology   (Ono Pharmaceutical)   03-Jun-2008
Updated CDX-110 Data in Glioblastoma Multiforme Presented at 44th Annual ASCO Annual Meeting   (Pfizer)   02-Jun-2008
Cell Genesys Reports Updated Results From Phase 1 Clinical Trial of GVAX Immunotherapy for Prostate Cancer Used in Combination With Ipilimumab   (Cell Genesys)   02-Jun-2008
Interim Phase 1/2 Data of Ipilimumab in Prostate Cancer Presented at American Society of Clinical Oncology Annual Meeting   (Medarex)   02-Jun-2008
Preliminary Data from Ongoing Phase 1 Data of Investigational Anti-PD-1 Antibody Presented at American Society of Clinical Oncology Annual Meeting   (Medarex)   02-Jun-2008
New Ipilimumab Survival Data in Patients with Metastatic Melanoma Presented at American Society of Clinical Oncology Annual Meeting   (Bristol-Myers Squibb)   01-Jun-2008
New Ipilimumab Survival Data in Patients with Metastatic Melanoma Presented at American Society of Clinical Oncology Annual Meeting   (Medarex)   01-Jun-2008
Ipilimumab Plus Chemotherapy is Associated with Prolonged Survival and Increased Disease Control Rates in Patients with Advanced Melanoma   (Medarex)   01-Jun-2008
Genmab Initiates Zalutumumab Combination Study in Colorectal Cancer   (Genmab)   30-May-2008
Genmab Announces Updates on Phase III Cancer Studies   (Genmab)   29-May-2008
Medarex Reports Phase 1 Clinical Data of MDX-1100 at Digestive Disease Week   (Medarex)   21-May-2008
Medarex Announces Initiation of Phase 2 Clinical Trials for the Treatment of Ulcerative Colitis and Rheumatoid Arthritis   (Medarex)   12-May-2008
Confidence in Medarex's ipilimumab dented again   (Medarex)   28-Apr-2008
Medarex and Bristol-Myers Squibb Joint Statement on Submission Status of Ipilimumab   (Medarex)   25-Apr-2008
Medarex and Bristol-Myers Squibb Joint Statement on Submission Status of Ipilimumab   (Bristol-Myers Squibb)   25-Apr-2008
Medarex Reports Phase 1/2 Clinical Data of MDX-060 in Lymphoma at American Association for Cancer Research Meeting   (Medarex)   16-Apr-2008
Medarex Reports Preclinical Data on Multiple Antibody-Drug Conjugate Candidates at American Association for Cancer Research Meeting   (Medarex)   16-Apr-2008
Novel Insights into HuMax-EGFr Mechanisms of Action Published in PNAS   (Genmab)   15-Apr-2008
Cell Genesys Reports Data on an Association Between Immune Response and Anti-Tumor Activity in Patients Receiving GVAX Immunotherapy for Prostate Cancer and Ipilimumab (MDX-010)   (Cell Genesys)   15-Apr-2008
Significant Tumor-Specific Immune Response Observed in AVANT's Phase 2 Trial Evaluating CDX-110 with Temozolomide for Treatment of Glioblastoma Multiforme   (AVANT Immunotherapeutics)   15-Apr-2008
Medarex Reports Interim Data from Ongoing Ipilimumab Combination Phase 1 Studies in Prostate Cancer at American Association for Cancer Research Meeting   (Medarex)   15-Apr-2008
ACZ885, a New Biological Drug in Development, Shows Potential in Treating Serious Life-long Autoinflammatory Diseases   (Novartis)   08-Apr-2008
Medarex Announces Ipilimumab Program Continues to Move Forward   (Medarex)   03-Apr-2008
Pfizer's melanoma disappointment compounds Medarex misery   (Medarex)   02-Apr-2008
Medarex to Receive Milestone Payment from Novo Nordisk   (Medarex)   31-Mar-2008
Medarex Receives Milestone Payment for Submission of Regulatory Application Requesting Approval of Golimumab (CNTO 148) in Europe for the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis   (Medarex)   20-Mar-2008
Centocor, Inc. and Schering-Plough Submit Application Requesting Approval of Golimumab in Europe for the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis   (Schering-Plough)   18-Mar-2008
Centocor, Inc. and Schering-Plough Submit Application Requesting Approval of Golimumab In Europe For the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis   (Johnson & Johnson)   18-Mar-2008
Novel Anti-CD20 Monoclonal Antibody Ofatumumab Demonstrates Anti-Tumour Responses in Patients With Relapsed/Refractory B-Cell Chronic Lymphocytic Leukaemia   (GlaxoSmithKline)   08-Feb-2008
Centocor Announces Ustekinumab Biologic License Application Accepted For Filing By FDA   (Johnson & Johnson)   04-Feb-2008
Promising Phase 3 Data for Ustekinumab (CNTO 1275) in Long-Term Improvement of Chronic Plaque Psoriasis   (Johnson & Johnson)   04-Feb-2008
Medarex Announces Allowance of Investigational New Drug Application for Wholly Owned Fully Human Anti-CD70 Antibody, MDX-1411   (Medarex)   08-Jan-2008
Medarex to Receive Milestone Payment from Amgen   (Medarex)   18-Dec-2007
Genmab Announces Details of Planned Ofatumumab Phase II Study in Multiple Sclerosis   (Genmab)   13-Dec-2007
Genmab Initiates Ofatumumab Phase II Study in Diffuse Large B-Cell Lymphoma   (Genmab)   13-Dec-2007
One more throw of the dice for ipilimumab   (Medarex)   12-Dec-2007
Top-Line Data Available from Three Ipilimumab Pivotal Trials in Patients with Advanced Metastatic Melanoma   (Medarex)   10-Dec-2007
Top-Line Data Available from Three Ipilimumab Pivotal Trials in Patients with Advanced Metastatic Melanoma   (Bristol-Myers Squibb)   10-Dec-2007
Medarex to Receive Milestone Payment for Submission of Regulatory Applications Requesting Approval of Ustekinumab (CNTO 1275) for Treatment of Psoriasis   (Medarex)   07-Dec-2007
Centocor and Janssen-Cilag Submit Applications Requesting Approval of Ustekinumab in the U.S. and Europe for Treatment of Moderate to Severe Plaque Psoriasis   (Johnson & Johnson)   04-Dec-2007
Medarex Announces Allowance of Investigational New Drug Applications for Wholly Owned Fully Human Anti-CD19 Antibody, MDX-1342   (Medarex)   04-Dec-2007
Genmab Announces Update on Recruitment of Patients in Ofatumumab CLL Pivotal Study   (Genmab)   28-Nov-2007
GlaxoSmithKline and Genmab Initiate Ofatumumab Rheumatoid Arthritis Phase III Programme   (GlaxoSmithKline)   20-Nov-2007
FibroGen Announces New Research in HIF and CTGF Therapeutic Programs Presented at the Annual Meeting of the American Society of Nephrology   (FibroGen)   08-Nov-2007
Medarex Announces Presentations on UltiMAb(R) Antibodies at 71st Annual Meeting of the American College of Rheumatology   (Medarex)   08-Nov-2007
FibroGen Announces New Research in HIF and CTGF Therapeutic Programs Presented at the Annual Meeting of the American Society of Nephrology   (FibroGen)   07-Nov-2007
Initiation of Development of “ONO-4538/MDX-1106”, Fully Human Anti-PD-1 Antibody for Hepatitis C in US   (Ono Pharmaceutical)   30-Oct-2007
Ono and Medarex Announce Allowance of Investigational New Drug Application for Fully Human Anti-PD1 Antibody   (Medarex)   29-Oct-2007
Genmab’s HuMax-CD4 Displays Unique Mechanism of Action   (Genmab)   15-Oct-2007
Genmab Amends HuMax-CD4 Pivotal Study in CTCL   (Genmab)   11-Oct-2007
Genmab Amends Ofatumumab Pivotal Study in NHL to Single Arm Study   (Genmab)   27-Sep-2007
DAHANCA Initiates Head and Neck Cancer Study With Genmab’s HuMax-EGFr   (Genmab)   13-Sep-2007
Genmab Discloses Target and Development Plans for HuMax-Inflam   (Genmab)   13-Sep-2007
Genmab Announces Encouraging Preclinical Data for Ofatumumab   (Genmab)   07-Sep-2007
Preliminary Data Add New Mechanistic Insights to Activity of Anthrax Anti-Toxin, Valortim(TM)   (Medarex)   31-Jul-2007
Medarex Announces Advancement of Antibody Development by Partner   (Medarex)   19-Jul-2007
MedImmune Advances Potential Treatment for Patients With Lupus   (AstraZeneca)   19-Jul-2007
Medarex Announces Initiation by Licensing Partner of Phase III Clinical Trial for Muckle Wells Syndrome   (Medarex)   18-Jul-2007
Anti-TNF Golimumab Continues to Show Promise in Phase II Rheumatoid Arthritis Study   (Schering-Plough)   14-Jun-2007

IN-DEPTH COMPETITIVE INTELLIGENCE AVAILABLE ON

 
  Product Generic Name
Medarex aB7H4 -
  ACZ885 -
  ADC Research Program -
  AFP-VAC -
  ALT-212 -
  AMG 714 -
  Amgen Antibody-1 -
  Amgen Antibody-2 -
  Amgen Antibody-3 -
  Amgen Antibody-4 -
  Amgen Antibody-5 -
  Anti-bacterial MAb -
  Anti-cancer MAb -
  Anti-SDF-1 MAb -
  aPtk7 -
  ARIUS/Medarex Cancer Research Project -
  AutoImmune MAb Collaboration -
  Avalon cancer antibody collaboration -
  BMS-66513 -
  Cancer antibody collaboration -
  Cancer MAb Project -
  Cancer Research Project -
  CDX-110 -
  CDX-1307 -
  CDX-1401 -
  CDX-2101 (inc. Ribi-529 adjuvant) -
  CDX-2301 -
  CDX-2401 -
  CDX-2410 -
  CDX-S03 -
  CNTO 1275 ustekinumab
  CNTO 148 golimumab
  CNTO 95 -
  COL-VAC -
  Compugen antibody collaboration -
  CP-675,206 tremelimumab
  DTS-201 -
  Duocarmycin B2 -
  Eos/Medarex/Biosite Cancer MAb -
  Euroscreen MAb collaboration -
  FG-3019 -
  Fully-Human RSV MAbs -
  GVHD-TOX -
  Haematological cancer MAb collaboration -
  HGS-TR2J -
  HuMax-CD20 ofatumumab
  HuMax-CD4 zanolimumab
  HuMax-EGFr zalutumumab
  HuMax-Inflam (MDX-018) -
  IL-13 Antibody -
  IMC-18F1 -
  IMC-3G3 -
  Immunology MAb collaboration -
  Infectious Disease Research Project -
  Ipilimumab ipilimumab
  KW-2189 pibrozelesin
  LOR-A04 -
  Lung Cancer MAb -
  MAb Research Project -
  MAGE3 -
  MDX 1097 -
  MDX-060 iratumumab
  MDX-066 -
  MDX-067 -
  MDX-070 -
  MDX-11 -
  MDX-1100 -
  MDX-1185 -
  MDX-1342 -
  MDX-1388 -
  MDX-1401 -
  MDX-1411 -
  MDX-214 -
  MDX-22 -
  MDX-220 -
  MDX-240 -
  MDX-33 -
  MDX-44 -
  MDX-447 -
  MDX-RA -
  Medarex/Raven MAb -
  MEDI-545 -
  MEDI-546 -
  MelanA -
  MEL-VAC -
  NI-0401 -
  Novartis Antibody 2 -
  NY-ESO-1 -
  OGeS cancer antibody collaboration -
  ONO-4538 / MDX-1106 -
  Organon/Medarex MAb -
  Osidem -
  Ovarian Cancer MAb -
  PSA-VAC -
  SARS MAb -
  Second-generation MDX-070 toxin conjugate -
  Valortim -
  VAP-1 Antibody Program -
 
EvaluatePharma® provides historic and forecast sales from 1986 to 2012 for worldwide and US Rx (prescription drugs) and OTC drugs. EvaluatePharma® analysts continuously update company models from SEC filings, annual reports, investor/analyst presentations, company press releases, FDA and USPTO. Consensus forecasts for marketed and emerging products are built-up using recent research reports from top equity analysts.

Analyse pharma and biotech products by market status or development phase (e.g., preclinical, phase I, phase II, phase III, filed, approved, withdrawn, disposed etc), therapeutic category, product sourcing strategy, patent expiry and patent life remaining, originator, technology, indication, pharmacological class, deal dates, deal types and partners, launch dates, FDA approval data and new molecular entity (NME) age - plus many more data items and analytics unique to EvaluatePharma®.

Aggregations of these measures at a high-level means that companies may be ranked against each other on items such as: market capitalization, patent risk, R&D spend, freshness index, sales strategy (inlicensed vs organic sales), sales by therapy area or technology and various other concentration measures. These aggregations make EvaluatePharma® ideal for competitive benchmarking, ranking and Peer Group analysis.

Note: When a merger or acquisition is agreed, a virtual merged Company will be added to the list of available Company reports. Any information presented for a virtual merged company is for illustrative purposes, only.

Source: EvaluatePharma ® Generated at 14:11:14 (GMT) on 11-Jun-2008 © 2008 EvaluatePharma Ltd