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Celgene 
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A small selected sample of reports and related news headlines for Celgene are available below. Free sample reports are also available for other Companies.

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CONSENSUS FORECASTS ($US mln) -  Sales Forecasts available to EvaluatePharma Subscribers

  Annual Sales WW - Sales Growth per Year (%)
  Rank Product Generic Name Pharmacological Class 2006 2007 2007
Celgene 1 Revlimid lenalidomide Immunomodulator 321 774   141%  
  2 Thalomid thalidomide Angiogenesis inhibitor 433 447   3%  
  3 Alkeran melphalan Alkylating agent 50 74   46%  
 
  Note: Shaded Cells  

PIPELINE ANALYSIS - Sales Forecasts available to EvaluatePharma Subscribers

 
  Rank Product Therapeutic Category Therapeutic Subcategory Pharmacological Class Phase (Current)
Celgene - Actimid (CC-4047) Oncology & Immunomodulators Other cytostatics Immunomodulator Phase II
  - CC-8490 Oncology & Immunomodulators Hormone therapies Benzopyran Phase II
  - CC-10004 Dermatology Anti-psoriasis agents Phosphodiesterase IV inhibitor Phase II

DEALS - Selected Company Deals

 
  Rank Deal Date Deal Type Product Status on Deal Date Deal Partner/ Product Source Deal Value
Celgene 1 Feb 2008 In-licensed ACE-011 Phase I Acceleron Pharma 567
  2 Feb 2008 In-licensed Cancer-related Bone Loss Research Program Phase I Acceleron Pharma 437
  3 Aug 2007 In-licensed Sirtuin inhibitor program Research project MethylGene 106

FINANCIAL DATA ($US mln) - Forecasts available to EvaluatePharma Subscribers

Celgene
  2005 2006
 Valuation Measures
  Based on Latest Share Prices
     Valuing the Equity
       Market Capitalisation 26,540 26,540
       PE Ratio (diluted) - Normalised (x) 349.1 318.6
 
     Valuing the Enterprise
       Enterprise Value 23,998 23,998
       Free Cash Flow (Pre-Dividends) 12 31
       FCF Yield (%) 0.1% 0.1%
 
 Forecast Financials
  Income Statement
     Total Revenues 537 899
     Cost of Goods Sold (81) (125)
     S,G & A (179) (340)
     R&D (191) (246)
     Other Income/ Expense - Net 6 6
     Associate/ Equity Affiliate Income (7) (8)
     EBIT - Normalised 85 185
     Net Interest & Financial Items 15 31
     Pre-tax Profits - Normalised 100 216
     Exceptionals (16) (13)
     Income Before Taxes 84 203
     Tax (21) (134)
     Tax Rate (%) 24.4% 66.0%
     Net Income - Reported 64 69
     Net Income - Normalised 68 78
 
  Per Share Data
     EPS - Diluted 0.16 0.17
     EPS - Basic 0.19 0.20
     EPS - Normalised (diluted) 0.17 0.19
     EPS - Normalised (basic) 0.20 0.22
     Avg. Shares Outstanding - Diluted 390.6 407.2
     Avg. Shares Outstanding - Basic 335.5 352.2
     DPS 0.00 0.00

NEWS - Selected Product News Headlines (as of 11 June 2008)

Study of VIDAZA(R) in Higher-Risk Myelodysplastic Syndrome Patients Demonstrates Improved Overall Survival   (Celgene)   03-Jun-2008
Methylgene Reports Clinical Data From a Phase II Study Evaluating MGCD0103 in Relapsed or Refractory Non-Hodgkin Lymphomas at the 44th American Society of Clinical Oncology (ASCO) Annual Meeting   (MethylGene)   03-Jun-2008
Data from Studies of Amrubicin in Small-Cell Lung Cancer Presented at the 2008 American Society of Clinical Oncology Meeting Demonstrate Single Agent Anti-Tumor Activity in Western Patient Population   (Celgene)   02-Jun-2008
Celgene Withdraws European Union (EU) Marketing Authorization Application for Lenalidomide in Deletion-5Q Myelodysplastic Syndromes   (Celgene)   02-Jun-2008
New Data from Several Satraplatin Clinical Trials in Solid Tumors Presented at 44th ASCO Annual Meeting   (GPC Biotech)   02-Jun-2008
MethylGene Reports Clinical Data for MGCD0103 at the 44th American Society of Clinical Oncology (ASCO) Annual Meeting   (MethylGene)   02-Jun-2008
Data from Satraplatin SPARC Phase 3 Trial in Patients with Hormone-Refractory Prostate Cancer Progressing after Initial Chemotherapy Presented at 44th ASCO Annual Meeting   (GPC Biotech)   02-Jun-2008
Updated REVLIMID(R) Data Presented in Newly Diagnosed Multiple Myeloma Presented at the 2008 American Society of Clinical Oncology (ASCO) Meeting   (Celgene)   01-Jun-2008
Updated REVLIMID(R) Results Presented In Relapsed/Refractory Aggressive Non-Hodgkin's Lymphoma (NHL) at ASCO   (Celgene)   01-Jun-2008
Clinical Data for MethylGene's MGCD0103 to be Presented at the 2008 American Society of Clinical Oncology Annual Meeting   (MethylGene)   16-May-2008
Celgene Cellular Therapeutics Announces Clinical Transplant of Human Placenta-Derived Stem Cells   (Celgene)   02-May-2008
Thalidomide Pharmion(TM) Granted Full Marketing Authorization for Treatment of Newly Diagnosed Multiple Myeloma in the European Union   (Celgene)   21-Apr-2008
MethylGene Provides Update on Its MGCD0103 Hdac Inhibitor Collaboration With Celgene   (MethylGene)   15-Apr-2008
MethylGene Presents Clinical Biomarker Data for MGCD0103 and Preclinical Efficacy Data in Combination With Taxanes at AACR Annual Meeting   (MethylGene)   14-Apr-2008
Amrubicinis Designated as an Orphan Medicinal Product by the European Commission for the Treatment of Small Cell Lung Cancer   (Celgene)   11-Apr-2008
Thalidomide Pharmion(R) Receives Marketing Approval from Australian Therapeutic Goods Administration for Treatment of Newly Diagnosed Multiple Myeloma   (Celgene)   07-Apr-2008
Amrubicin(R) Receives FDA Orphan Drug Designation for the Treatment of Small Cell Lung Cancer   (Celgene)   25-Mar-2008
Seattle Genetics Initiates SGN-33 Clinical Trial in Combination with Revlimid(R) for Myelodysplastic Syndromes (MDS)   (Seattle Genetics)   20-Mar-2008
Pharmacopeia Collaboration with Celgene Corporation Advances Compound Into Phase 1 Clinical Development   (Pharmacopeia)   05-Mar-2008
Lenalidomide (REVLIMID(R)) Receives Orphan Drug Status in Japan for Multiple Indications   (Celgene)   19-Feb-2008
Pharmion and MethylGene Announce U.S. Orphan Drug Designation Granted for MGCD0103 for the Treatment of Acute Myelogenous Leukemia   (Pharmion)   14-Feb-2008
MethylGene and Pharmion Announce U.S. Orphan Drug Designation Granted for MGCD0103 for the Treatment of Acute Myelogenous Leukemia   (MethylGene)   14-Feb-2008
Millennium must work hard for Velcade advantage   (Millennium Pharmaceuticals)   12-Feb-2008
Pharmion and MethylGene Announce Orphan Drug Designation Granted by the European Medicines Agency (EMEA) for MGCD0103 for the Treatment of Acute Myelogenous Leukemia   (Pharmion)   11-Feb-2008
MethylGene and Pharmion Announce Orphan Drug Designation Granted by the European Medicines Agency (EMEA) for MGCD0103 for the Treatment of Acute Myelogenous   (MethylGene)   11-Feb-2008
Pharmion shareholder raises the stakes   (Pharmion)   08-Feb-2008
EMEA Accepts for Review Vidaza(R) Marketing Authorization Application for Higher-Risk Myelodysplastic Syndromes   (Pharmion)   07-Feb-2008
Clinical Data Reported on Celgene Compound Apremilast (CC-10004) Evaluating Efficacy, Safety and Quality of Life Improvement for Psoriasis Patients   (Celgene)   04-Feb-2008
MethylGene Reports MGCD0103 Clinical Data at the 2008 Gastrointestinal Cancers Symposium   (MethylGene)   28-Jan-2008
Celgene Reports on REVLIMID(R) (Lenalidomide) Global Regulatory Developments in Multiple Myeloma and Deletion 5Q Myelodysplastic Syndromes   (Celgene)   24-Jan-2008
Thalidomide Pharmion(R) Receives Positive Opinion for Treatment of First-line Multiple Myeloma from European Medicines Agency   (Pharmion)   24-Jan-2008
Pharmion Submits European Marketing Authorization Application (MAA) for Vidaza(R) in Patients with Higher-Risk Myelodysplastic Syndromes (MDS)   (Pharmion)   14-Jan-2008
Pharmion and MethylGene Start Phase 2 Combination Clinical Trial With MGCD0103 and Vidaza(R) in Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma   (Pharmion)   09-Jan-2008
MethylGene and Pharmion Start Phase II Combination Clinical Trial With MGCD0103 and Vidaza® in Patients With Relapsed Or Refractory Hodgkin Lymphoma Or Non-hodgkin Lymphoma   (MethylGene)   09-Jan-2008
MDS Patients on Five-Day Vidaza(R) Dosing Schedules Achieve Transfusion Independence Consistent with Seven-Day Schedule   (Pharmion)   11-Dec-2007
REVLIMID(R) (Lenalidomide) in Combination with Rituximab Demonstrates 70% Overall Response Rate in Hard to Treat Relapsed/Refractory Mantle Cell Lymphoma   (Celgene)   10-Dec-2007
Pharmion and MethylGene Present Favorable Clinical Data From Combination MGCD0103/Vidaza(R) Study in Myelodysplastic Syndromes and Acute Myelogenous Leukemia at The 49th American Society of Hematology (ASH) Meeting   (Pharmion)   10-Dec-2007
MethylGene and Pharmion Present Favorable Clinical Data from Combination MGCD0103/Vidaza® Study in Myelodysplastic Syndromes and Acute Myelogenous Leukemia at the 49th American Society of Hematology (ASH) Meeting   (MethylGene)   10-Dec-2007
Two Studies Demonstrate REVLIMID(R) (lenalidomide) Activity in Patients with Relapsed/Refractory Aggressive Non-Hodgkin's Lymphoma   (Celgene)   10-Dec-2007
SWOG Phase III Trial Reports REVLIMID(R) (lenalidomide) Plus Dexamethasone Achieves Superior Progression-Free Survival in Newly Diagnosed Multiple Myeloma Patients   (Celgene)   09-Dec-2007
Pharmion and Methylgene Report Favorable Results for Phase 2 MGCD0103 Single- Agent Studies in Relapsed or Refractory Lymphomas at the 49th American Society of Hematology (ASH) Meeting   (Pharmion)   09-Dec-2007
Thalidomide Added to Standard Therapy Prolongs Overall Survival in Newly Diagnosed Multiple Myeloma Patients Over Age 75   (Pharmion)   09-Dec-2007
Pharmion Presents Clinical Data Demonstrating Significant Survival Advantage of Vidaza(R) in Patients with Myelodysplastic Syndromes (MDS)   (Pharmion)   09-Dec-2007
MethylGene and Pharmion Report Favorable Results for Phase II MGCD0103 Single-agent Studies in Relapsed or Refractory Lymphomas at the 49th American Society of Hematology (ASH) Meeting   (MethylGene)   09-Dec-2007
REVLIMID(R) (Lenalidomide) Plus Low-Dose Dexamethasone Achieves Unprecedented Survival Rate in ECOG Phase III Trial in Newly Diagnosed Multiple Myeloma   (Celgene)   09-Dec-2007
Pharmion to Present Clinical Data on Key Hematology Products at American Society of Hematology (ASH) Annual Meeting   (Pharmion)   06-Dec-2007
Lenalidomide (REVLIMID(R)) Receives Orphan Medicinal Product Designation from the European Commission for Chronic Lymphocytic Leukemia   (Celgene)   30-Nov-2007
Updated REVLIMID(R) (Lenalidomide) Plus Dexamethasone Data in Previously Treated Multiple Myeloma Reported in The New England Journal of Medicine   (Celgene)   21-Nov-2007
Two Major Phase III Studies Report Oral REVLIMID(R) (Lenalidomide) Plus Dexamethasone Shows Increased Overall Survival Advantage to Dexamethasone Plus Placebo in Previously Treated Multiple Myeloma Patients in The New England Journal of Medicine   (Celgene)   21-Nov-2007
Cancer Drug REVLIMID(R) Receives Recommendation for Approval from Australian Drug Evaluation Committee for Treatment of Multiple Myeloma   (Celgene)   12-Nov-2007
Pharmion's Amrubicin Shows Encouraging Results Compared to Standard of Care in Second Line Treatment of Small Cell Lung Cancer   (Pharmion)   09-Nov-2007
GPC, Pharmion's phase III failure could raise eyebrows at Poniard   (GPC Biotech)   31-Oct-2007
Pharmion and GPC Biotech Announce Results of Overall Survival Analysis From the Satraplatin Pivotal Phase 3 Trial   (Pharmion)   30-Oct-2007
GPC Biotech and Pharmion Announce Results of Overall Survival Analysis from the Satraplatin Pivotal Phase 3 Trial   (GPC Biotech)   30-Oct-2007
Pharmion and MethylGene Report Preliminary MGCD0103 Clinical Data at the 2007 AACR-NCI-EORTC International Conference   (Pharmion)   24-Oct-2007
MethylGene and Pharmion Report Preliminary MGCD0103 Clinical Data at the 2007 AACR-NCI-EORTC International Conference   (MethylGene)   24-Oct-2007
Pharmion Initiates Pivotal Phase 3 Study of Amrubicin in Small Cell Lung Cancer   (Pharmion)   17-Oct-2007
Pharmion and MethylGene Initiate Phase One Combination Clinical Trial with MGCD0103 and Taxotere(R) in Patients with Solid Tumors   (Pharmion)   10-Oct-2007
MethylGene and Pharmion Initiate Phase I Combination Clinical Trial With MGCD0103 and Taxotere® in Patients With Solid Tumors   (MethylGene)   10-Oct-2007
Pharmion and MethylGene Announce Orphan Drug Designation Granted by the European Medicines Agency (EMEA) for MGCD0103 for the Treatment of Hodgkin's Lymphoma   (Pharmion)   24-Sep-2007
MethylGene and Pharmion Announce Orphan Drug Designation Granted by the European Medicines Agency (EMEA) for MGCD0103 for the Treatment of Hodgkin's Lymphoma   (MethylGene)   24-Sep-2007
Updated REVLIMID(R) Clinical Results Presented at the 12th International Workshop on Chronic Lymphocytic Leukemia   (Celgene)   17-Sep-2007
Oral Cancer Drug REVLIMID® Receives Swissmedic Approval in Switzerland For Treatment of Multiple Myeloma   (Celgene)   04-Sep-2007
Pharmion's Oral Azacitidine Granted Fast Track Status for Myelodysplastic Syndromes   (Pharmion)   29-Aug-2007
Pharmion and MethylGene Announce U.S. Orphan Drug Designation Granted for MGCD0103 for the Treatment of Hodgkin's Lymphoma   (Pharmion)   21-Aug-2007
MethylGene and Pharmion Announce U.S.Orphan Drug Designation Granted for MGCD0103 for the Treatment of Hodgkin's Lymphoma   (MethylGene)   21-Aug-2007
Vidaza Significantly Extends Overall Survival by 74% in Phase 3 Trial in Myelodysplastic Syndromes (MDS)   (Pharmion)   02-Aug-2007
Marketing Authorization Application for Satraplatin Accepted for Review by the European Medicines Agency   (Spectrum Pharmaceuticals)   27-Jul-2007
MethylGene Initiates Single-agent Phase II Clinical Trial With Its HDAC Inhibitor, MGCD0103, in Patients With Refractory Chronic Lymphocytic Leukemia   (MethylGene)   12-Jul-2007
GPC Biotech Announces that Partner Pharmion Submits European Marketing Application for Satraplatin   (GPC Biotech)   26-Jun-2007
Pharmion Submits European Marketing Authorization Application for Satraplatin in Combination with Prednisone for the Treatment of Patients with Metastatic Hormone-Refractory Prostate Cancer Who Have Failed Prior Chemotherapy   (Pharmion)   26-Jun-2007
Marketing Authorization Application Filed for Satraplatin With the European Medicines Agency   (Spectrum Pharmaceuticals)   26-Jun-2007
REVLIMID(R) Granted Full Marketing Authorization for Treatment of Multiple Myeloma in the European Union   (Celgene)   19-Jun-2007

IN-DEPTH COMPETITIVE INTELLIGENCE AVAILABLE ON

 
  Product Generic Name
Celgene ACE-011 -
  Actimid (CC-4047) pomalidomide
  Alkeran melphalan
  Biovance -
  Calsed amrubicin
  Cancer-related Bone Loss Research Program -
  CC-0227113 -
  CC-10004 apremilast
  CC-10015 -
  CC-1088 -
  CC-11006 -
  CC-11050 -
  CC-13097 -
  CC-132889 -
  CC-15965 -
  CC-16057 -
  CC-25493 -
  CC-359 (JNK 359) -
  CC-401 (JNK 401) -
  CC-4089 -
  CC-5048 -
  CC-7085 -
  CC-8490 -
  CC-930 (JNK 930) -
  Cord Blood Cells -
  Cytogen Ligase Research Project -
  E2 Ligase Inhibitors -
  Focalin/Focalin XR dexmethylphenidate
  Gelclair sodium hyaluronate & polyvinylpyrrolidone
  HDAC Inhibitor (2nd generation) -
  HPDSC Transplants -
  IKK-2 Inhbitor (CC-24839) -
  Innohep tinzaparin
  MGCD0103 -
  MKK Inhibitor -
  Orplatna satraplatin
  PDA-001 -
  PLR-11 -
  PS873266 -
  Refludan lepirudin
  Revlimid lenalidomide
  Ritalin/Ritalin LA methylphenidate
  SERM-beta -
  Sirtuin inhibitor program -
  SP600125 -
  SPC 401 -
  SPC9766 -
  Thalomid thalidomide
  Tubulin Inhibitor -
  Vidaza azacitidine
 
EvaluatePharma® provides historic and forecast sales from 1986 to 2012 for worldwide and US Rx (prescription drugs) and OTC drugs. EvaluatePharma® analysts continuously update company models from SEC filings, annual reports, investor/analyst presentations, company press releases, FDA and USPTO. Consensus forecasts for marketed and emerging products are built-up using recent research reports from top equity analysts.

Analyse pharma and biotech products by market status or development phase (e.g., preclinical, phase I, phase II, phase III, filed, approved, withdrawn, disposed etc), therapeutic category, product sourcing strategy, patent expiry and patent life remaining, originator, technology, indication, pharmacological class, deal dates, deal types and partners, launch dates, FDA approval data and new molecular entity (NME) age - plus many more data items and analytics unique to EvaluatePharma®.

Aggregations of these measures at a high-level means that companies may be ranked against each other on items such as: market capitalization, patent risk, R&D spend, freshness index, sales strategy (inlicensed vs organic sales), sales by therapy area or technology and various other concentration measures. These aggregations make EvaluatePharma® ideal for competitive benchmarking, ranking and Peer Group analysis.

Note: When a merger or acquisition is agreed, a virtual merged Company will be added to the list of available Company reports. Any information presented for a virtual merged company is for illustrative purposes, only.

Source: EvaluatePharma ® Generated at 13:59:28 (GMT) on 11-Jun-2008 © 2008 EvaluatePharma Ltd