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Actelion 
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A small selected sample of reports and related news headlines for Actelion are available below. Free sample reports are also available for other Companies.

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CONSENSUS FORECASTS ($US mln) -  Sales Forecasts available to EvaluatePharma Subscribers

  Annual Sales WW - Sales Growth per Year (%)
  Rank Product Generic Name Pharmacological Class 2006 2007 2007
Actelion 1 Tracleer bosentan Endothelin A & B receptor antagonist 718 983   37%  
  2 Ventavis iloprost Prostacyclin analogue - 65   n/a  
  3 Zavesca miglustat Glucosyltransferase inhibitor 20 29   45%  
 
  Note: Shaded Cells  

PIPELINE ANALYSIS - Sales Forecasts available to EvaluatePharma Subscribers

 
  Rank Product Therapeutic Category Therapeutic Subcategory Pharmacological Class Phase (Current)
Actelion 1 Almorexant (ACT-078573) Central Nervous System Sedatives & hypnotics Orexin receptor antagonist Phase III
  2 Actelion-1 (ACT-064992) Cardiovascular Other anti-hypertensives Endothelin receptor antagonist Phase III
  3 Pivlaz Cardiovascular Cerebral & peripheral vasotherapeutics Endothelin A receptor antagonist Phase III

FINANCIAL DATA ($US mln) - Forecasts available to EvaluatePharma Subscribers

Actelion
  2005 2006
 Valuation Measures
  Based on Latest Share Prices
     Valuing the Equity
       Market Capitalisation 6,799 6,799
       PE Ratio (diluted) - Normalised (x) 61.7 33.2
 
     Valuing the Enterprise
       Enterprise Value 6,613 6,613
       Free Cash Flow (Pre-Dividends) 87 239
       FCF Yield (%) 1.3% 3.6%
 
 Forecast Financials
  Income Statement
     Total Revenues 533 755
     Cost of Goods Sold (53) (72)
     S,G & A (219) (296)
     R&D (138) (169)
     Other Income/ Expense - Net (2) (4)
     EBIT - Normalised 122 214
     Net Interest & Financial Items (13) 8
     Pre-tax Profits - Normalised 109 223
     Exceptionals 0 0
     Income Before Taxes 109 223
     Tax (8) (30)
     Tax Rate (%) 7.7% 13.5%
     Net Income - Reported 101 193
     Net Income - Normalised 101 193
 
  Per Share Data
     EPS - Diluted 0.90 1.67
     EPS - Basic 0.90 1.70
     EPS - Normalised (diluted) 0.90 1.68
     EPS - Normalised (basic) 0.90 1.70
     Avg. Shares Outstanding - Diluted 112.0 114.9
     Avg. Shares Outstanding - Basic 111.6 113.3
     DPS 0.00 0.00

NEWS - Selected Product News Headlines (as of 11 June 2008)

United Therapeutics' Viveta to challenge Actelion's Ventavis   (United Therapeutics)   15-May-2008
Actelion Enters Phase III with Novel Orexin Receptor Antagonist Almorexant   (Actelion)   20-Dec-2007
Phase III Study Initiated With Actelion-1   (Actelion)   19-Dec-2007
Actelion Provides Update on Bosentan in Metastatic Melanoma   (Actelion)   17-Dec-2007
Actelion/Merck & Co., Inc. Renin Alliance Achieves Fourth Milestone   (Actelion)   05-Dec-2007
Pivlaz® (clazosentan) Phase III Study Initiated to Demonstrate Prevention of Vasospasm-Related Morbidity and All-Cause Mortality After Aneurysmal Subarachnoid Hemorrhage   (Actelion)   12-Nov-2007
Miglustat (Zavesca®) Receives Negative Opinion from the European Committee for Medicinal Products for Human Use for Extension of Indication for Niemann Pick type C   (Actelion)   19-Oct-2007
Miglustat Enters Phase IIa for Cystic Fibrosis   (Actelion)   28-Sep-2007
EARLY: First PAH Functional Class II Population Study Emphasizes Need to Diagnose and Treat PAH Early   (Actelion)   03-Sep-2007
New Data on Orexin Receptor Antagonist Almorexant Shows Therapeutic Potential to Restore Normal Physiological Sleep in Patients Suffering from Insomnia   (Actelion)   02-Sep-2007
Bosentan (Tracleer®) Receives EU Approval for Reduction of Number of New Digital Ulcerations in Systemic Sclerosis Patients   (Actelion)   12-Jun-2007

IN-DEPTH COMPETITIVE INTELLIGENCE AVAILABLE ON

 
  Product Generic Name
Actelion Actelion-1 (ACT-064992) -
  Actelion-10 (ACT-AB-2) -
  Actelion-11 (ACT-AB-3) -
  Actelion-3 -
  Actelion-4 -
  Actelion-5 -
  Actelion-6 -
  Actelion-7 -
  Actelion-8 -
  Actelion-9 (ACT-AB-1) -
  ACT-S1P1 (Actelion-2/R3477) -
  Almorexant (ACT-078573) almorexant
  Axovan 1 -
  Axovan 3 -
  BACE-1 Inhibitor project -
  Cancer project -
  Fasudil fasudil
  Malaria project -
  MK-8141 -
  NS-304 -
  Palosuran (ACT-058362) palosuran
  Pivlaz clazosentan
  TNKase tenecteplase
  Tracleer bosentan
  Veletri tezosentan
  Ventavis iloprost
  Zavesca miglustat
 
EvaluatePharma® provides historic and forecast sales from 1986 to 2012 for worldwide and US Rx (prescription drugs) and OTC drugs. EvaluatePharma® analysts continuously update company models from SEC filings, annual reports, investor/analyst presentations, company press releases, FDA and USPTO. Consensus forecasts for marketed and emerging products are built-up using recent research reports from top equity analysts.

Analyse pharma and biotech products by market status or development phase (e.g., preclinical, phase I, phase II, phase III, filed, approved, withdrawn, disposed etc), therapeutic category, product sourcing strategy, patent expiry and patent life remaining, originator, technology, indication, pharmacological class, deal dates, deal types and partners, launch dates, FDA approval data and new molecular entity (NME) age - plus many more data items and analytics unique to EvaluatePharma®.

Aggregations of these measures at a high-level means that companies may be ranked against each other on items such as: market capitalization, patent risk, R&D spend, freshness index, sales strategy (inlicensed vs organic sales), sales by therapy area or technology and various other concentration measures. These aggregations make EvaluatePharma® ideal for competitive benchmarking, ranking and Peer Group analysis.

Note: When a merger or acquisition is agreed, a virtual merged Company will be added to the list of available Company reports. Any information presented for a virtual merged company is for illustrative purposes, only.

Source: EvaluatePharma ® Generated at 13:52:10 (GMT) on 11-Jun-2008 © 2008 EvaluatePharma Ltd